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Estriol succinate : ウィキペディア英語版
Estriol

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Estriol (also oestriol or E3) is one of the three main estrogens produced by the human body.
==Biosynthesis==

Estriol is only produced in significant amounts during pregnancy as it is made by the placenta from 16-hydroxydehydroepiandrosterone sulfate (16-OH DHEAS), an androgen steroid made in the fetal liver and adrenal glands.
The human placenta produces pregnenolone and progesterone from circulating cholesterol. Pregnenolone is converted in the fetal adrenal gland into dehydroepiandrosterone (DHEA), a C19 steroid, then subsequently sulfonated to dehydroepiandrosterone sulfate (DHEAS). DHEAS is converted to ''16-OH DHEAS'' in the fetal liver. The placenta converts 16-OH DHEAS to estriol, and is the predominant site of estriol synthesis.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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